Analyses were performed using GWAS data from subtypes of bipolar disorder (BD1, BD2, SAB) and major depressive disorder (rMDD, sMDD, subMDD). SNP-based heritability for the subtypes ranged from subMDD and sMDD (8%), through BD2 and rMDD (10% and 12%, respectively) to BD1 and SAB (22% and 29% respectively, Figure 2, Supplementary Table 2).