of some MGE- and CGE-derived cortical interneurons (cINs), olfactory bulb interneurons, striatal projection neurons, retinal cells, prethalamic reticular nucleus cells and inhibitory cells derived from the zona limitans (zli) (Supplementary Fig. 3). Cortical interneurons are conventionally categorized based on neuropeptide and Ca2+ binding protein expression16. Of those markers, we found that somatostatin (SST) was most highly expressed; calbindin (CB or CALB1), calretinin (CR or CALB2), and neuropeptide Y (NPY) were also robustly detected; little parvalbumin (PV) or vasoactive intestinal polypeptide (VIP) was detected (Supplementary Fig. 3). Thus, mRNA profiling suggests that AMD-iN cells resemble forebrain GABAergic neurons derived from the ganglionic eminences.
