For the current analyses, we employ principal analytic approaches that represent only one of many current approaches to analyzing GWA data (see discussion above, also at www.nhlbi.nih.gov/resources/listserv/number35.htm (RFA-HL-07-010); [6, 85]. Despite this limitation, the replicated positive results obtained here and the failure of control experiments to support alternative hypotheses do provide significant confidence in roles for most of the genes reported.
