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Chunk #13 — Possibility 1: Alcohol as a Breast Tumor Promoter — The Estrogen Hypothesis and its Complications

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Moderate alcohol consumption and breast cancer in women: from epidemiology to mechanisms and interventions.
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The authors found that daily consumption of 15 g of ethanol/day did not significantly increase serum levels of any estrogens. The only hormone that was significantly elevated was dehydroepiandrosterone sulfate (DHEAS), which is an androgen primarily secreted by the adrenal gland. In women drinking 30 g of ethanol/day, DHEAS levels were elevated along with those of estrone sulfate. Notably, the most biologically potent estrogen, estradiol, was not elevated by either dose of alcohol.