Chunk #14 — Possibility 1: Alcohol as a Breast Tumor Promoter — The Estrogen Hypothesis and its Complications

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Moderate alcohol consumption and breast cancer in women: from epidemiology to mechanisms and interventions.

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The Dorgan study design left open the possibility that acute alcohol drinking could transiently increase estrogen levels. However, in another interventional study, Ginsburg et al found no effect of acute ethanol on serum estradiol levels in postmenopausal women not taking hormone replacement therapy (HRT) (Ginsburg et al., 1996).