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Chunk #29 — Results — VBM Analysis

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Functional and Structural Alteration of Default Mode, Executive Control, and Salience Networks in Alcohol Use Disorder.
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The AUD group had lower gray matter volume in the three networks than the healthy control group: (1) the ACC, mPFC, SMA (t = 2.180, P < 0.05) in the anterior SN; (2) the left thalamus (t = 2.025, P < 0.05), left lobule VI (t = 2.104, P < 0.05), and right posterior insula (t = 2.946, P < 0.05) in the posterior SN; (3) the mPFC, ACC, orbitofrontal cortex (t = 2.117, P < 0.05), left hippocampus (t = 2.896, P < 0.05), and right hippocampus (t = 2.828, P < 0.05) in the dorsal DMN; (4) the left parahippocampal gyrus (t = 2.943, P < 0.05), right parahippocampal gyrus (t = 2.633, P < 0.05), and right lobule IX (t = 2.100, P < 0.05) in the ventral DMN; (5) the left middle frontal gyrus, superior frontal gyrus (t = 2.281, P < 0.05), and left inferior frontal gyrus and orbitofrontal gyrus (t = 2.811, P < 0.05) in the left ECN; and (6) the left crus I, II, lobule VI (t = 2.491, P < 0.05)