108 loci were identified as associated with schizophrenia in a case-control meta-analysis including 150,064 individuals. For the current study, the 46 case-control cohorts of European ancestry were retained, totaling 33,640 cases and 43,546 controls. Cases were defined as individuals diagnosed with schizophrenia or schizoaffective disorder, which was determined by research-based assessment or clinician diagnosis depending on the sample.
