The GWS risk loci identified by previous OD GWAS (e.g., KCNG2, CNIH3, and RGMA)7–10 were not concordant with the present investigation (Supplementary Table 10). Such discrepancies are not unexpected, given that these analyses were underpowered, and the reported findings are likely to be affected by phenotypic heterogeneity and the random variation allowing for discovery of alternate subsets of risk loci in small datasets55, 56.
