Efforts to include representative numbers of Blacks in biomedical research have been met with some difficulty, with successful recruitment usually entailing careful planning, extensive community engagement, time, and human resources (Shavers et al., 2002; Clay et al., 2005). The usual explanations for this difficulty typically involve mistrust, which is thought to be more prevalent among Blacks compared with Whites, because of the well-known historical legacy of the Tuskegee Syphilis Study, among others (Schulz et al., 2003; Bates and Harris, 2004).
