Chunk #18 — METHODS — THE CORRECTION OF TYPE 1 ERROR FOR ALLELIC ASSOCIATION TESTING

Source

Case-control association testing in the presence of unknown relationships.

Embedded

yes

Text

The corrected χ2 test can be easily extended to the multiallelic case and under the null distribution, the test statistic asymptotically follows a χ2 distribution with (a − 1) degrees of freedom, where a is the number of alleles, as described previously [Bourgain et al., 2003].