A total of 407 abstracts were screened for the PAE literature, with 17 meeting inclusion criteria; 145 abstracts were screened for the COA, with 37 meeting criteria. Several studies were excluded because they used symptom count, latent class or factor analysis, severity scores, or some other quantitative measure of the behavioral disorders. Other studies were excluded because the comparison group was ascertained on a specific characteristic (e.g., PAE with ADHD vs ADHD alone), did not assess PAE or parental alcohol dependence, was ascertained on a broader substance dependence criteria, or had a small sample size (total N < 20). The final sample consisted of 24 ORs from 17 independent studies in the PAE domain, and 62 ORs from 32 independent studies in the COA domain, with several studies reporting on more than one disorder, or reporting on both maternal and paternal alcohol dependence (Tables S1 and S2).
