Chunk #20 — Discussion

Source

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

Embedded

yes

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Association with total antioxidants was shown for a variant in PCSK2, a proprotein convertase that is involved in proteolytic processing of neuropeptide and hormone precursors. PCSK2 is highly expressed in the islets of Langerhans, where it plays a role in the conversion of proinsulin to insulin.