An independent GWAS was run at 23andMe using logistic regression assuming an additive model for allelic effects, while covarying for age, sex, 4 principal components and array platform, followed by SNP lookups of our 221 independent GWS SNPs. The phenotype was identical to that reported from9 (discussed in detail in the section above) but consisting of an entirely independent sample of 455,350 cases and 887,428 (n=1,342,778) not previously included in any reported primary analysis.
