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Chunk #12 — 4. Discussion

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Gender Differences and Comorbidities in U.S. Adults with Bipolar Disorder.
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This study of population-based hospital data from patients with bipolar disorder reveals the association with various medical and psychiatric comorbidities and gender differences. Hypertension was the most common comorbidity in bipolar patients (20.5%), but was lower when compared to the general global population, as mentioned in a systematic study from 2000–2010 (28.5% in high-income countries and 31.5% in low- and middle-income countries) [9] and the recent report stating that hypertension is seen in 30.2% of men and 27.7% of women in the general population [10]. Many psychotropic medications such as tricyclic antidepressants can induce hypotension, which can mask the symptoms of hypertension during routine health check-ups. Thus, the number of hypertensive patients with bipolar disorder could potentially be lower [11]. Another possible reason for the lower number of bipolar patients with hypertension could be due to fewer follow-up visits of mental and behavioral patients to the primary health clinics [12]. As per the Global Asthma Report, about 8.6% of young adults (age 18–45) experienced the symptoms of asthma in 2014, whereas comorbid asthma was seen in a higher proportion of