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Chunk #40 — Discussion — Theoretical Implications

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Subjective response to alcohol challenge: a quantitative review.
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Moreover, research capitalizing on the increasing availability of genotyping techniques presents another promising avenue for identifying the physiological and neurological underpinnings of these subjective responses. Some studies have identified candidate genes related to subjective stimulant (e.g., Ray and Hutchison, 2004; Ray et al., 2010) and sedative responses (e.g., Corbin et al., 2006; Hinkers et al., 2006; Hu et al., 2005; Lind et al., 2008; Schuckit et al., 1999). In addition to providing evidence that subjective stimulant and sedative responses to alcohol may be inherited risk factors, this line of research has the potential to clarify the ways in which the two responses are similar and distinct.