significant SNPs, only rs9636470 in PLGLB2 (p=2.4×10-6 in EAs and 0.004 in AAs) and rs1318937 in SH3BP5 (p=2.5×10-5 in EAs and 0.005 in AAs) were replicable between two populations. However, rs9636470 in PLGLB2 was the only replicable significant SNP in a 3Mb-wide region around this gene, and thus, this significant association could occur by chance. In contrast, the region around SH3BP5 was enriched with replicable risk SNPs and thus was the focus of interest in the present study.
