aspects of drinking reaction related to SRE-5 versus SRE-T (i.e., more sensitivity for the former but both sensitivity and intersession tolerance for the latter) are hypothetical and difficult to prove. Fifth, it is important to remember that a person’s response to alcohol can be measured several ways (King et al., 2014; Schuckit, 2018), including the level of stimulation experienced early in a drinking occasion which is also related to future escalations in drinking quantities and problems (King et al., 2014). Alcohol stimulation during rising blood alcohol concentrations (BACs) cannot be measured with the SRE. Sixth, the sample reported on here is modest in size, and some of the non-significant findings in Tables 3 and 4 might be significant in larger studies. Finally, the heritability estimates for same-sex siblings offered here do not fully consider the impact of shared family environment.
