Chunk #49 — ONLINE METHODS — Data acquisition, quality control, and normalization — QTL Sharing.

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Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.

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We used the Storey’s π1 statistics63 also described in Nica et al.64, QTL sharing was estimated as the proportion of true associations π1 among the top SNP in each QTLs in the second QTL.