Maternal substance use during pregnancy data were also analyzed by trimester. High-risk mothers were more likely to use alcohol and cigarettes and to consume these substances in greater quantities during each trimester (all p<.01). High-risk mothers who drank during pregnancy consumed an average of 12.71 drinks per week in the first trimester (n=57), 5.81 per week in the second trimester (n=31), and 5.09 per week in the third trimester (n=32). Low-risk mothers who drank during pregnancy consumed an average of 1.60 drinks per week in the first trimester (n=19), 0.44 per week in the second trimester (n=7), and 0.41 per week in the third trimester (n=8). High-risk mothers who smoked cigarettes during pregnancy consumed an average of 5.24 packs per week in the first trimester (n=60), 4.78 packs per week in the second trimester (n=54), and 4.71 packs per week in the third trimester (n=53). Low-risk mothers who smoked cigarettes during pregnancy consumed an average of 3.46 packs per week in the first trimester (n=15), 3.91 packs per week in the second trimester (n=9), and 3.51 packs per week in the third trimester (n=8).