Chunk #39 — PGC, an agenda

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Psychiatric Genomics: An Update and an Agenda.

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Actionability. For the common variant aims, Aim 1 is of biological, clinical, and therapeutic relevance. Aim 2 and Aim 3 are important clinically and for nosology. Of the rare variant aims, all are important biologically and therapeutically (given their potential to identify single genes whose mutational disruption carries high risk).