the PTSD-alcohol comorbidity literature with few exceptions (Mallard et al., 2021). Finally, this study attempts to examine whether findings are consistent between those of European Ancestry (EA) and African Ancestry (AA) individuals – the latter of which is particularly important given the lack of diversity in genomic studies (Bentley, Callier, & Rotimi, 2017; Peterson et al., 2019; Sirugo, Williams, & Tishkoff, 2019). This study leverages large-scale GWASs summary statistics from a number of consortia [i.e. Psychiatric Genomics Consortium (PGC)-PTSD and Substance Use Disorder (SUD)-AD, United Kingdom Biobank (UKB), Million Veterans Program (MVP), 23andMe, and GWAS & Sequencing Consortia of Alcohol and Nicotine Use (GSCAN)].
