PTSD case/control status came from the PGC-PTSD Freeze 2 dataset (PTSD), which consists of over 50 separate datasets plus the UKB (Nievergelt et al., 2019). In analyses utilizing alcohol use data from the UKB, PGC-PTSD PTSD case status reflects primarily lifetime PTSD diagnosis, but also includes current diagnosis when lifetime was not available (30 of 57 cohorts in Freeze 2 provided lifetime data). PGC-PTSD case/control status data were available for both EA and AA samples. PGC-PTSD Freeze 2 were used instead of Freeze 1.5 because of the increase in sample size and inclusion of AA individuals (EA: Total PTSDf1.5 N = 48 471; PTSDf2.0 N = 174 659; AA: Total PTSDf2.0 N = 15 339) (Nievergelt et al., 2019).
