Since the graphs show cumulative effects, the indications of significant difference at the bottom of each graph do not record the onset of the occurrence of the genotypic effect; the onset occurs earlier, perhaps at the time when the value of the effect size curve is near zero and the slope of the effect size curve increases in absolute value. This is difficult to quantify exactly, as the onset of genotypic effect is subject to the same uncertainty as the estimation of the ranges of significant effect. Similarly, the cessation of genotypic effect probably occurs by the time the effect size curve reaches an extremum.
