Finally, women admissions accounted for 27% of cannabis-involved treatment admissions in the TEDS report (SAMHSA, 2015). Similarly, we found lower odds of CU and CUD among women than men. However, women with a CUD tended to have comorbid depressive/anxiety problems, and they might present more severe cannabis withdrawal systems than men (Compton et al., 2004. Herrmann et al., 2015; Khan et al., 2013). Given that cannabis withdrawal systems are related to relapse and common outcome measures in studies of pharmacotherapies for cannabis dependence (Marshall et al., 2014), sex differences in comorbidities and manifestations of CUD symptoms warrant research to inform sex-specific or tailored treatments for CUD.
