h2 = 9.21%, P = 1.39 × 10−67; PCL-Total conditioned h2 = 4.11%, P = 2.61 × 10−52) relative to the unconditioned GWAS (Pdifference = 1.52 × 10−13), but this reduction in heritability did not significantly alter associations with biological pathways or tissues associated with genetic risk for PTSD as evidenced by linear relationships between tissue and pathway enrichment effects (Extended Data Fig. 4).
