Two SNPs for Openness to Experience on chromosome 5q14.3 and one SNP for Conscientiousness on chromosome 18q21.1 passed the genome-wide significance level of P < 5 × 10−8 in the discovery stage (Table 3). The genome-wide meta-analyzed association results for the five personality dimensions are given in Supplementary Figure 2. Top SNPs for Neuroticism, Extraversion and Agreeableness (Supplementary Tables 2 to 6) did not reach genome-wide significance (lowest P value > 10−8).