whereas males showed no differences (all p’s>0.34). Given the association of these alleles with Impulsiveness, we examined whether Insula activation was also related to Impulsiveness. Indeed, Impulsiveness was correlated with left insula activation during reward anticipation (r2 = 0.399; p = 0.026) and loss anticipation (r2 = 0.361; p = 0.046). Impulsiveness and right insula activation approached significant correlation during reward anticipation (r2 = 0.338; p = 0.063) and was significantly correlated during loss anticipation (r2 = 0.373; p = 0.039). There were no significant differences between COA and controls or for gender for these correlations.
