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Chunk #1 — INTRODUCTION

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The genetics of substance dependence.
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yes

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In the 2010 SAMHSA survey (119a), approximately 58.3 million Americans aged 12 or older reported being current cigarette smokers, and a recent Surgeon General’s report (129) indicated that one-third of people who have tried smoking became daily smokers (defined as those who reported that they have smoked 100 or more cigarettes during their lifetime and currently smoke every day or some days). The SAMHSA survey (119a) also showed that 59.6% of current smokers aged 12 or older smoked daily and that this proportion increased with age---going from 16.5% among those aged 12–17, to 27.8% among those aged 18–25, to 48.9% among those aged 26 or older. The detrimental effects of tobacco use or exposure to secondhand smoke include an increased risk of cancer, chronic lung disease, heart disease, and stroke. In the United States, cigarette smoking accounts for 30% of deaths from cancer and nearly 80% of deaths from chronic obstructive pulmonary disease (COPD) (22, 95), and it is also the primary causal factor for early cardiovascular disease and deaths (22). Globally, cigarette smoking kills 5.4 million people every year and accounts for 10% of adult deaths (144).