As exploratory analyses, we also completed whole brain analyses as contrasts for both task conditions which are presented in Figure 8 and Figure 9 and Table 6 and Table 7. During the viewing of masked angry faces, non-marijuana smoking control subjects demonstrated significant differences relative to the chronic, heavy marijuana smokers (see Table 6) in the cingulate gyrus (peak x, y, z = −2, 20, 30; t = 3.82, p< 0.05; k = 125) as well as regions in the left and right parietal lobe (see Figure 8a). In contrast, the chronic, heavy marijuana smokers demonstrated activity within primarily temporal, parietal and frontal regions, though these were less focal than those demonstrated by the non-marijuana smoking controls (see Figure 8b, Table 6). During the viewing of masked happy faces, non-marijuana smoking control subjects demonstrated significant differences relative to the chronic, heavy marijuana smokers (see Figure 9a, Table 7) in the superior temporal gyrus and sublobar space, while the chronic, heavy marijuana smokers demonstrated significant differences within the posterior lobe (see Figure 9b, Table 7).
