Chunk #12 — Results — Haplotype analysis

Source

Association of amyloid precursor protein-binding protein, family B, member 1 with nicotine dependence in African and European American smokers.

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The last significant haplotype, C-T-G, consisting of rs10839562-rs1079199-rs8164, showed negative associations with all three ND measures for all three samples. However, only the association in the EA sample with a frequency of 57.7% and a Z score of −2.55 (P = 0.011, 70 informative families) remained significant with HSI after Bonferroni correction.