ND measure in each of the three samples. For example, this haplotype was significantly associated with SQ in the AA sample under both the additive (Z = −2.67; P = 0.008, 128 informative families) and dominant models (Z = −2.75; P = 0.006, 125 informative families), and with HSI under the recessive model in the EA sample (Z = −2.62; P = 0.009, 52 informative families) with a frequency of 47.5%. In the pooled sample, under the additive model, its Z score was −2.80 (P = 0.005, 235 informative families) for HSI and −2.95 (P = 0.003, 233 informative families) for SQ.
