for eQTL enrichment using data from LCLs will ultimately yield such evidence when data from more relevant tissues is used; alternatively, at least a subset of those disorders without evidence for enrichment for eQTLs may turn out to derive substantial heritability from rare variants. In any case, results of our studies clearly support additional investment in eQTL identification in other tissues, as well as in the development of public access databases and software tools, such as those in SCAN (http://www.scandb.org), that allows results of such studies to be productively used by the scientific community.
