4), and the addition of information from the genetic risk function produced a net reclassification improvement of 4.6% (−2.0% to 11.3%) (P=0.17) (web table L). Neither the simple gene count score (net reclassification improvement 0.2%, −5.1 to 4.7) (table 5) nor the genetic risk function (net reclassification improvement −3.2%, −9.9 to 3.5) (web table M) resulted in a net reclassification improvement when added to the Framingham offspring risk score.
