Two closely mapped chromosome 2 SNPs, rs7371606 and rs925966, were associated with AD at P < 4 × 10−8 in EAs. They map between DARS (aspartyl-tRNA synthetase) and CXCR4 (chemokine (C-X-C motif) receptor 4), and are distant from both. Several markers spanning <3500 bp on chromosome 5p (minimal P = 8.59 × 10−9 at rs1493464) in a ‘gene desert’ were associated in AAs. A common intergenic chromosome 9 SNP, rs1856202, was associated in AAs (P = 5.99 × 10−11) and a common intronic SNP in DPP9 (dipeptidylpeptidase 9), rs113683471, was associated in EAs (P = 2.89 × 10−8) (Table 2, Figure 2).
