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Chunk #19 — RESULTS — Case–control analysis

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Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.
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Case–control analysis identified GWS association with many of the SNPs in ADH1B and LOC100507053 that were identified by ordinal analysis, but the results were not as robust (Supplementary Table S2). Although there were no well-supported GWS findings outside of this region, some evidence of association (P < 1 × 10−6) was observed with SNPs at 19 other loci, including rs99998785, which is ~17 kb from a (GWS) SNP (rs925966) in the ordinal trait analyses.