For the biological annotation of the 20 SNPs in Table 1, we generated a list of LD partners for each of the original SNPs. A SNP was considered an LD partner for the original SNP if (i) its pairwise LD with the original SNP exceeded R2 = 0.6 and (ii) it was located within 250kb of the original SNP. We also generated a list of genes residing within loci tagged by our lead SNPs (Supplementary Table 34).