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Chunk #17 — Results — Study of Fkbp5 Expression in Rodents

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Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans.
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Interaction effects between ELS and ethanol drinking were observed in the VTA (F = 4.35, p = .043, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ {\eta}_p^2 $$\end{document}ηp2 = .090) and Acb (F = 5.16, p = .028, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ {\eta}_p^2 $$\end{document}ηp2 = .103) (Fig. S4), but not in other regions except a trend in the Ccx (p = 0.098) (data not shown). Regarding correlations of Fkbp5 expression in different regions, a positive correlation was observed between mPFC and Amy (r s = .740, p < .001) as well as between mPFC and CCx (r s = .626, p = .003) in alcohol-drinking MS360, but not MS15, rats. Correlations that did not pass Bonferroni correction are reported in the Table S3 (non-significant correlations are not reported).