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Chunk #34 — Discussion

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Absence of P300 reduction in South African treatment-naïve adolescents with alcohol dependence.
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yes

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Regarding associations between P300 and (a) family history density of alcohol problems, and (b) psychiatric symptom counts, we observed only one significant relationship (a positive association between P3a latency and internalizing symptoms). Although genetic risk for alcoholism and the presence of other psychopathology have known effects on the P300 (Hill et al., 1999a, 2000; Perlman et al., 2009), the low levels and limited range of scores on measures of these variables in the current sample probably prevented us from observing other possible significant associations with ERP measures.