frequency of RNA vs DNA and the read depth for four representative SNPs with significant differential expression in both cell lines are shown in Figure 1B. Relaxing the FDR to < 0.2, there were 102 functional SNPs in SH-SY5Y and 128 in SK-N-BE(2), among which 57 SNPs showed significant differential expression in both cell lines, 51 in the same direction (Table 1; Table 2). Allele-biased expression results can be visualized on an R-shiny-based interactive website (https://yunlongliulab.shinyapps.io/coga_passport/).
