Functional networks are spatially distributed sets of brain regions that exhibit temporally correlated activity. Studies have shown that these networks are evident even in the brain’s intrinsic activity during the resting state, termed resting-state functional connectivity [rsFC; 8, 9]. fMRI studies have consistently observed disruptions in the default mode network (DMN) and the fronto-parietal network (FPN) in individuals with depression [4]. The DMN is comprised of regions that exhibit greater activity under task-free conditions relative to conditions requiring goal-directed behavior [10] and include the medial prefrontal cortex, the posterior cingulate cortex and precuneus, as well as bilateral inferior temporo-parietal cortexes and medial temporal lobes [11]. This network is thought to subserve self-referential processing, memory and the allocation of attentional resources for cognitive processing [11]. In contrast, the FPN includes a set of brain regions involved in the top-down modulation of attention and emotion and includes portions of the lateral prefrontal cortex and posterior parietal cortex. The FPN is implicated in cognitive control [12], and inhibits the DMN when it is irrelevant to task performance [13]. In the context of depression,
