One motivation for the current project is to facilitate rapid evaluation of whether polymorphisms implicated in human disease influence gene expression or splicing in relevant tissue types. We have therefore established a user interface called SNPExpress, which permits rapid interrogation of the localized effects of common SNPs on exon and transcript level expression (Figure 5). This resource is freely available at: http://people.genome.duke.edu/∼dg48/SNPExpress/.
