We also assessed transcript-level associations for proximity of LD regions associated with the eQTL to promoter regions (within 10 kb upstream of the transcript start) or in the 3′UTR regions of transcripts, key regions involved in transcription and stability of mRNA transcripts [11]. Twenty-one out of 23 high confidence eQTLs or SNPS in the LD region (r 2 > 0.2) were found to be located in or extending beyond these relevant regions involved in the steady state expression level of mRNA transcripts.
