The association of AFD with the incidence of alcohol abuse was not modified by either age or gender. Neither were the associations of AFD with the incidence of individual abuse criteria modified by age; however, there was a significant interaction (p=.034) between gender and initiation of drinking at ages 15-17 for recurrent drinking in hazardous situations (OR = 1.65 for females but nonsignificant for males, data not shown).
