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Chunk #25 — RESULTS — Consumption as a mediator and moderator of associations with AFD

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Age at first drink and the first incidence of adult-onset DSM-IV alcohol use disorders.
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As shown in Table 3, all of the associations between AFD and the incidence AUD and specific AUD criteria lost statistical significance after adjusting for average daily volume of ethanol consumption. Interestingly, early initiation of drinking showed a negative association with the incidence of impaired control (desire or unsuccessful attempts to stop or cut down on drinking) after adjusting for consumption, and this association was statistically significant when the AFD categories of <15 and 15-17 were combined (OR = 0.85, p=.044, data not shown).