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Chunk #26 — RESULTS — Consumption as a mediator and moderator of associations with AFD

Source
Age at first drink and the first incidence of adult-onset DSM-IV alcohol use disorders.
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Reflecting a negative interaction between volume of consumption and AFD, the incidence of drinking more/longer than intended was significantly reduced among individuals with AFD at ages15-17 who consumed the equivalent of two or more standard drinks per day. A similar interaction was observed for the incidence of withdrawal, but the reduction in risk at heavy volumes of consumption failed to reach statistical significance.