Pooled DNA of 7 samples was used as negative control. A combination of five ChIP-seq quality measures were employed to detect low quality samples: samples that did not reach (i)≥15×106 uniquely mapped unique reads, (ii) non-redundant fraction≥0.3, (iii) cross correlation≥0.03, (iv) fraction of reads in peaks≥0.05 and (v)≥6000 peaks were removed.