integrated fashion to influence behavioral responses to alcohol? (iv) Do the genes alter alcohol-related behavioral responses via a common set of neuronal or other cellular mechanisms? (v) What are the major areas of the nervous system in which the genes function and what neurotransmitter systems are modulated by the genes? (vi) Do the genes influence alcohol-related behavior by functioning in non-neuronal cells? (vii) Do the genes influence multiple behavioral responses to alcohol similarly? (viii) Are the gene products direct pharmacological targets of alcohol? (ix) What is the complete complement of genes that is required for normal behavioral responses to alcohol? Flies and worms have contributed substantially to the field, yet much work remains to be done in iMOs on the genetics of alcohol-related behavior.
