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Chunk #8 — METHODS — Single cell enrichment in post-mortem brain tissue of suicide deaths

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A Multivariate Genomic Investigation of the Externalizing Spectrum and Suicide Risk.
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variance with the candidate genes. Next, we normalized both the raw disease (e.g., suicide) and control scores for each cell, resulting in normalized disease and control scores. We evaluated cell type-level associations to identify broad cell types linked to the disease-status and to examine variability across individual cells within each cell type. All results were adjusted for multiple testing using a false discovery rate (FDR)44.