Variants identified through GWAS are not necessarily causal and typically tag a region of association containing potential causal variant(s). The Catalog data are used to investigate the region of association tagged by a GWAS variant and to prioritize potential causal variants for fine mapping. Therefore, a new interactive query and visualization of the variant's genomic context and linkage disequilibrium in 50 kb window is calculated (as r2 or D’) for HapMap (30) and 1000 Genomes (31) populations. Variants are coloured using the same scheme as the karyotype diagram allowing easy visualization of traits (Figure 4).
