association formation processes. Additionally, non-AU youth showed greater BOLD response than the AU youth to alcohol versus control pictures in only two regions (right middle frontal gyrus and right IFG). Notably, in the AU youth, greater quantity of AU per month was positively correlated with BOLD response in task-relevant regions including the left inferior frontal, left paracentral lobule/dorsal cingulate, right precuneus/cuneus, right precuneus/posterior cingulate. In addition, within the AU group, higher BOLD signal in response to alcohol versus control cues was correlated with desire to drink across task-relevant frontal and visual regions including the left superior frontal gyrus, right precentral gyrus, right postcentral gyrus, right paracentral lobule, right superior parietal lobule, fusiform gyri and lingual gyri. In addition, an inverse relationship between BOLD response and desire to drink was observed for the task-relevant craving-based region of the left ventral anterior cingulate.
